
Focus on AI infrastructure over application-layer SaaS, as companies like Mercor are seeing massive growth by providing the high-quality data and human expertise required to train frontier models. Consider long-term positions in "Frontier Labs" like OpenAI and Anthropic, which are projected to reach valuations as high as $10 trillion as they become the essential "teacher models" for the entire industry. While NVIDIA (NVDA) remains a core holding, prepare for a multi-chip future by monitoring emerging competitors like Cerebras and in-house chip projects from Meta and Google. Prioritize investments in AI Security and "agentic trust" platforms like Vanta to capitalize on the urgent corporate need to defend against automated, agent-led cyber attacks. Look for opportunities in the "Token Spend" shift, where enterprise budgets are moving away from human headcount and toward massive compute and inference consumption via platforms like Airwallex.

By Harry Stebbings
The Twenty Minute VC (20VC) interviews the world's greatest venture capitalists with prior guests including Sequoia's Doug Leone and Benchmark's Bill Gurley. Once per week, 20VC Host, Harry Stebbings is also joined by one of the great founders of our time with prior founder episodes from Spotify's Daniel Ek, Linkedin's Reid Hoffman, and Snowflake's Frank Slootman. If you would like to see more of The Twenty Minute VC (20VC), head to www.20vc.com for more information on the podcast, show notes, resources and more.