Annie Lamont is Co-Founder and Managing Partner of Oak HC/FT, the healthcare and fintech investment firm she built with Andrew Adams. Across 40+ years she has managed $14B, backed 70+ successful exits and 15 IPOs, and been named the top healthcare investor on the Forbes Midas List multiple times. Her portfolio includes athenahealth, Devoted Health, One Medical, CareBridge, VillageMD, Main Street Health, Komodo Health, and Chai Discovery.
Recorded at the New York Stock Exchange, the conversation covers China taking 50% of pharma's outside research dollars, clinical trial reform at the FDA, and Chai Discovery's roadmap from antibodies to peptides to small molecules. Lamont also explains how AI can cut the 25% to 30% of healthcare costs that are administrative.
On the investing side, she walks through backing repeat founders Todd Park and Brad Smith, CareBridge's acquisition by Elevance, Oak's $1M to $100M check sizes across a $2B fund, and newer portfolio companies Halluminate and Auger. The episode closes with the Brex Performance segment on mentors.
"I just think you've got 10% of the world that's worth it & 90% that's not."
We cover:
› Why AI drug discovery changed in the last 2 years
› China's rise in life sciences
› Devoted Health tripling in size and halving its operating ratio
› Why only 10% of AI companies justify their valuations
› Auger and Dave Clark's $100M AI supply chain build
Annie Lamont: https://x.com/annielamont
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(00:00) Annie Lamont, Co-Founder & MP at Oak HC/FT
(00:56) How AI reshaped the line between Healthcare and Fintech
(08:35) The China threat to American drug development
(17:03) Are Hospitals actually at risk from AI?
(23:26) How AI will transform your healthcare experience
(32:58) How M&A is changing in Healthcare
(50:26) What Halluminate actually does
(58:49) What's kept Annie Lamont going for four decades