3 businesses we think are about to blow up
3 businesses we think are about to blow up
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Note: AI-generated summary based on third-party content. Not financial advice. Read more.
Quick Insights
  • Treat oxytocin-based wellness and psychedelic treatments as speculative themes, not investment cases: the discussion cites no investable company, and clinical evidence, safety, and regulatory prospects remain uncertain.
  • Watch for opportunities in IVF, fertility preservation, and metabolic-health services, but the transcript names no specific companies or securities to buy.
  • Community-led membership businesses and values-based streaming may offer durable models, but the cited revenue and membership figures are unaudited and no public ticker or valuation is provided.
  • Avoid treating the discussion as a direct buy signal for Eli Lilly (LLY); it provides no price target, timeframe, or evidence to support an investment decision.
Detailed Analysis

Oxytocin-Based Relationship Wellness

  • Palmer Luckey’s proposed business idea is to use oxytocin alongside marriage counseling to help couples reconnect.
  • The hosts describe oxytocin as a hormone associated with bonding. They discuss small studies and online user journals suggesting it may affect social connection, but they also acknowledge that the evidence is limited and its effectiveness and safety are not established.
  • They speculate that a company could market oxytocin-based products or services for relationships, social connection, or team bonding. One host predicts such products could be advertised more widely within 12 months.
  • The transcript gives conflicting impressions of access and regulation: it describes oxytocin as “totally unregulated,” but also says a prescription may be needed for some products.

Takeaways

  • This is an early-stage, speculative health and wellness business theme, not a proven treatment or investment case.
  • A business opportunity would depend on credible evidence, safety, regulatory clarity, and responsible marketing—not anecdotes from forums or small studies.
  • The hosts’ discussion is not a recommendation to use oxytocin; the transcript itself emphasizes that efficacy and safety remain uncertain.

GLP-1s, TRT, IVF, and Fertility Services

  • The hosts cite GLP-1s, including Ozempic, and testosterone replacement therapy (TRT) as health trends they discussed early in their adoption cycles.
  • One host says they invested in an unnamed TRT business, but provides no company name, investment terms, or performance.
  • They also mention sperm freezing and IVF as growing areas of interest. A proposed opportunity is to build a trusted, multi-location IVF brand.
  • BPC-157 and peptides come up as an example of a once-fringe biohacking topic that the hosts say has become more common; no investment or medical recommendation is made.

Takeaways

  • The discussion points to potential business opportunities in metabolic health, hormone-related services, fertility preservation, and IVF.
  • The IVF idea is specifically about building a trusted service brand and chain, rather than identifying a particular company or security.
  • The transcript provides no company names, financial data, or specific investment recommendations for these themes, so it does not support a stock-level conclusion.

Psychedelic Treatments and Eli Lilly (LLY)

  • A host says a psychedelics company called “Attea Beckley” was acquired by Eli Lilly for about $2.8 billion, describing it elsewhere as a roughly $3 billion acquisition.
  • The hosts frame psychedelics as moving from a fringe category toward potential use in treating PTSD and trauma, while noting that some of the discussion is anecdotal.
  • No Lilly price target, investment timeline, or recommendation is given.

Takeaways

  • The conversation highlights growing interest in psychedelic-based mental-health treatments, but does not establish the clinical or commercial prospects of any specific product.
  • Treat the acquisition details as a claim made in the transcript; it gives no deal terms or supporting evidence to evaluate the transaction.
  • The discussion alone does not provide a basis for an investment decision in LLY.

Membership Communities and Financial Products

  • The hosts describe the Knights of Columbus as a long-running Catholic men’s fraternal organization with two to three million members, roughly $30 billion in assets, and insurance products for members. They say younger men are becoming its fastest-growing segment.
  • Good Sam is presented as an RV-owner membership that combines community and discounts with financial products, including RV insurance.
  • The USCCA is described as a membership organization for gun owners that offers training and insurance-related services; a host cites about $400 million in annual revenue.
  • AARP is offered as an example of a trusted membership brand that partners with providers to offer products such as health insurance, rather than necessarily underwriting them itself.
  • The proposed model is to build a community around a shared identity or interest, then earn revenue through dues, insurance, or other financial products.

Takeaways

  • The business theme is community-led distribution: a trusted group can attract and retain members, then connect them with relevant financial products.
  • The transcript suggests the model can be durable, but it does not provide comparable profitability, valuation, or investment data for these organizations.
  • Healthcare-sharing arrangements are specifically described as potentially less contractually guaranteed than conventional insurance, so the exact coverage and obligations matter.

Angel Studios and Values-Based Entertainment

  • Angel Studios is described as a streaming and production business focused on values-based content, with a membership community that can vote on projects.
  • The hosts cite approximately two to three million members, subscription prices of $13 to $20 per month, and around $400 million to $450 million in annual recurring revenue.
  • The transcript describes a model in which projects need strong member approval before the company proceeds with them.
  • The hosts present its audience focus and member participation as ways to differentiate it from mainstream studios.

Takeaways

  • The opportunity discussed is a subscription media business built around a clearly defined audience and community participation.
  • The membership base and revenue figures are claims made in the conversation; the transcript does not provide audited financials, costs, or valuation.
  • No ticker or specific investment recommendation is provided.

A24 and Film Production Economics

  • A24 is described as an independent studio that found room to make differentiated films while larger studios favored familiar franchises and broad-audience projects.
  • The hosts discuss unconventional marketing tactics, including social-media stunts and deliberately unusual promotional campaigns.
  • They describe film production as a hit-driven business: one project may succeed while many others fail. In one example, a film cost $14 million to make and $40 million to market. A hypothetical $250 million box office haul could leave about $125 million after theaters’ share, before considering other costs.
  • The hosts also note that some projects take years to develop, that marketing may cost more than production, and that a successful film’s proceeds may need to cover multiple failures.

Takeaways

  • The discussion suggests a potential edge for studios that can pair distinctive content with effective, lower-cost marketing, but success is difficult to predict.
  • Film investing carries the explicit risks of large marketing costs, uncertain audience demand, and a small number of hits supporting many unsuccessful projects.
  • The transcript does not identify A24 as a publicly traded investment or offer a stock recommendation.
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Video Description
*Database of 140+ business ideas:* https://clickhubspot.com/2blw Episode 868: Shaan Puri ( https://x.com/ShaanVP ) and Sam Parr ( https://x.com/theSamParr ) talk about 3 business ideas. — Show Notes: (3:08) Idea: Oxytocin dosing (20:17) Idea: Loneliness solutions (27:30) Idea: Faith-based businesses (27:33) Angel Studios (34:36) What’s the reaction to the action? (42:03) The brutal business of making hit movies — Links: • Anduril - https://www.anduril.com/ • Oculus - https://www.meta.com/quest/ • BlueChew - https://bluechew.com/ • Hims - https://www.hims.com/ • Beckley Psytech - https://www.beckleypsytech.com/ • Knights of Columbus - https://www.kofc.org/ • Good Sam - https://www.goodsam.com/ • AARP - https://www.aarp.org/ • Angel Studios - https://www.angel.com/ • The Chosen - https://www.thechosen.tv/ • A24 - https://a24films.com/ • Brick - https://getbrick.app/ • Grindr - https://www.grindr.com/ — Check Out Sam's Stuff: • Hampton (joinhampton.com): My community for founders. Average member does $25m/year. Many of the guests are members. Get after it...apply: http://joinhampton.com/mfm — Check Out Shaan's Stuff: • Shaan's weekly email - https://www.shaanpuri.com • Visit https://www.somewhere.com/mfm to hire worldwide talent like Shaan and get $500 off for being an MFM listener. Hire developers, assistants, marketing pros, sales teams and more for 80% less than US equivalents. • Mercury - Shaan uses Mercury across all of his companies. you can too: http://mercury.com/ Mercury is a fintech company, not an FDIC-insured bank. Banking services provided by Choice Financial Group, Column, N.A., Members FDIC • I run all my newsletters on Beehiiv and you should too + we're giving away $10k to our favorite newsletter, check it out: beehiiv.com/mfm-challenge My First Million is a HubSpot Original Podcast // Brought to you by HubSpot Media // Production by Arie Desormeaux // Editing by Ezra Bakker Trupiano /
About My First Million
My First Million

My First Million

By @myfirstmillionpod

two guys, talking about business. we've done it (sold our companies), and now we talk about new ideas, opportunities, and investments. hosted by Shaan Puri & Sam Parr -- produced by Hubspot. sometimes we bring on guests ranging from billionaires to stay at home moms who've got side hustles that are bringing in $10k a month. we like to have fun, and talk about business stuff.