Martin Shkreli

Buy oversold dips in Applied Optoelectronics (AAOI) following its recent capital raise, targeting a mean-reversion rebound toward the $115 to $118 range.

Establish a high-conviction speculative long position in Spruce Biosciences (SPRB), which offers 5x to 10x upside toward a $500 target as the market catches up to its rare disease drug pipeline.

Accumulate long-term exposure to the silicon photonics and optical components theme via data center suppliers Lumentum (LITE), Credo (CRDO), Fabrinet (FN), and Coherent (COHR) to ride AI infrastructure expansion.

Avoid long positions in Moderna (MRNA) and instead use temporary price rallies as short-selling opportunities given ongoing declines in vaccine demand.

Consider a tactical short-term dip buy on SanDisk around the $1,450–$1,460 level to capture an oversold bounce, keeping strict stop-losses in place to protect against broader semiconductor downturns.

• Consider shorting Moderna (MRNA) on upward price spikes, targeting a pullback into the $140 to $130 range as short-term buying momentum fades.
• In the semiconductor sector, initiate a pair trade by buying Intel (INTC) near the $90–$93 support level while shorting Broadcom (AVGO) as a relative valuation hedge.
• Take a contrarian long position in AppLovin (APP) to capture upside from its rapid revenue and earnings growth despite elevated short interest.
• Look to short Sellas Life Sciences (SLS) ahead of its binary clinical trial results over the next 4 to 6 weeks, while setting tight risk limits against potential short squeezes up to $20.
• Hedge existing technology portfolios against macroeconomic volatility by selectively shorting high-valuation software names like Palantir (PLTR), Datadog (DDOG), or Salesforce (CRM) once upward momentum stalls.

Traders can look to short Moderna (MRNA) following its overextended short-squeeze spike above $160, or alternatively buy Merck (MRK) as a lower-volatility way to gain exposure to their joint cancer vaccine breakthrough. Sellas Life Sciences (SLS) presents a high-conviction short opportunity ahead of its unpromising clinical trial readout expected between December and January, which carries severe downside risk toward zero. Investors should accumulate quality Enterprise Software leaders like ServiceNow (NOW) and Salesforce (CRM) as overblown fears of generative AI disruption begin to fade and clear the path for a recovery. For Nebius Group (NBIS), wait for the temporary arbitrage selling pressure from its convertible debt offering to settle before stepping in to buy the dip. In the semiconductor sector, favor Marvell Technology (MRVL) following its major custom silicon win with Google, while exercising caution on Broadcom (AVGO) due to customer diversification risks.

Consider buying shares of OmniAb (OABI) to capture significant long-term royalty upside tied to its high-potential drug candidate partnership with Johnson & Johnson. Take advantage of recent pullbacks in cloud infrastructure by dip-buying Microsoft (MSFT) and Oracle (ORCL) for an attractive rebound opportunity. Position for downside in SELLAS Life Sciences Group (SLS) ahead of its upcoming 80th clinical milestone readout, where expert sentiment indicates a low 25% probability of trial success. Target Cerebras Systems for a short-term mean-reversion trade to capitalize on an overextended 14% to 18% price surge that lacked a fundamental catalyst. Prepare to short SanDisk on signs of technical exhaustion, as the broader memory cycle appears near its peak and risks future supply saturation.

Capitalize on the artificial intelligence infrastructure boom by holding market leader NVIDIA (NVDA) as an essential long-term investment for your portfolio. Buy CoreWeave (CRWV) to capture explosive growth driven by massive enterprise demand, a $104 billion revenue backlog, and raised 2026 revenue guidance up to $13.2 billion. Accumulate shares of Lumentum Holdings (LITE) to benefit from robust optical networking demand, supported by strong gross margins and forward guidance of $1.225 billion. Trade SanDisk (SNDK) cautiously on a short-term basis while avoiding long-term positions due to looming structural price pressures from Chinese competitors. Approach Super Micro Computer (SMCI) with strict risk management as choppy trading persists following mixed quarterly results.

Consider buying Intel (INTC) as a potential long-term opportunity if you are comfortable with dilution risks tied to its massive infrastructure buildout. Anticipate and manage through historical volatility in NVIDIA (NVDA), utilizing its newly formed AI compute financing partnerships as a fundamental growth catalyst. Approach Palantir Technologies (PLTR) with extreme caution and look for short-term mean-reversion trades to fade overextended upward momentum. Aggressive short-term traders can target SanDisk (SNDI) on the short side with a price target between $1,100 and $1,300, banking on margin pressure from emerging Chinese competitors. Exercise strict risk management when shorting binary-outcome biotech plays like Silence Therapeutics (SLNS) or Apellis Pharmaceuticals (APRE) to avoid violent short squeezes from unexpected positive trial readouts.

Capitalize on natural price volatility by establishing a long position in Intel (INTC) to capture strong quarterly momentum and upward swings. Neutralize broader market risk by pairing your Intel holding with a tactical short position in Nvidia (NVDA) to hedge against semiconductor sector pullbacks. Exercise caution and strictly manage position sizes to avoid over-leveraging during volatile market sessions driven by macroeconomic news. Avoid speculative exposure to SanDisk, as it carries extreme downside beta and will suffer severe drawdowns if an artificial intelligence correction occurs.

Investors should watch for near-term downside volatility in SanDisk shares, as the market largely priced in its aggressive earnings beat and strong forward guidance. Long-term investors can view any post-earnings pullback in SanDisk as an opportunity to buy into its massive $93.9 billion data center pipeline and multi-year growth story. Capitalize on SanDisk's aggressive capital return strategy, backed by a newly authorized $14 billion share repurchase program. Traders should monitor Palantir (PLTR) for its historical post-earnings sell-off pattern to find a better entry window during the week following its report. Avoid making any immediate trades on Google (GOOGL), as current discussions lack fundamental catalysts or actionable price targets.

Capitalize on Intel's short-term momentum by buying dips and using disciplined limit orders around the psychological $100 level. Treat AMD as a high-beta trading vehicle for quick swings, keeping in mind that high-profile customer defections to Nvidia can create sudden downward pressure. Buy Taiwan Semiconductor (TSM) as a foundational, picks-and-shovels manufacturing play to safely capture broad semiconductor demand without betting on a single chip designer. Avoid shorting memory stocks like SanDisk heading into earnings events due to extreme binary volatility, and maintain strict caution with high-flying SpaceX shares as they approach the $110 level. Finally, exercise caution with enterprise software investments like Palantir, as emerging artificial intelligence tools threaten to compress traditional software margins.

Consider initiating a long position in Intel (INTC) to capitalize on potential mean reversion relative to the broader semiconductor sector. Avoid trading Micron (MU) zero-day-to-expiration (0 DTE) options due to extreme tail risk and high volatility. Be highly skeptical of short-term price spikes driven by promotional announcements, such as the recent NASDAQ partnership rally in Quantum / D-Wave (QBTS). Watch for tactical trading opportunities around corporate actions like debt exchanges, similar to recent events involving GameStop (GME). Finally, approach high-valuation stocks like Palantir (PLTR) with caution around earnings due to binary event volatility.

Capitalize on Amazon (AMZN) by leveraging its stellar AWS cloud growth for a strong long-term position despite recent trading volatility. Avoid secondary "NeoCloud" providers like Nebius (NEBIUS), as their heavy reliance on reselling third-party compute power presents high structural risks. Target heavily hyped, zero-revenue small-cap biotechs like Queue (Q) for lucrative short opportunities when retail chat room buzz outpaces weak fundamentals. Exercise caution and avoid Replimune (REPLI) despite its positive regulatory momentum, because real-world commercial adoption and doctor utility remain highly questionable. Finally, monitor fundamentally sound companies like AXTI (AXTI) for explosive short-term gains following major quarterly earnings beats.

Take advantage of the recent 9% post-earnings dip in Meta Platforms (META) to accumulate shares, as long-term growth fundamentals remain intact despite heavy artificial intelligence spending.

Prioritize Microsoft (MSFT) as a core tech holding due to its exceptional cloud execution, strong Azure growth, and disciplined capital expenditure strategy that continues to win over the market.

Trade the extreme volatility in Bloom Energy (BE) cautiously by capitalizing on momentum phases while strictly respecting cyclical peaks and potential valuation resets.

Utilize sharp relief rallies in Intel (INTC) for tactical short-term trades, but carefully weigh its cyclical valuation against forward earnings before making long-term commitments.

Look past near-term free cash flow pressures at Amazon (AMZN) and use infrastructure-driven pullbacks to buy, supported by robust 37% year-over-year growth in AWS.

Capitalize on the artificial intelligence boom by investing in NVIDIA ($NVDA**)**, which remains the foundational hardware backbone for the entire sector's expansion.

Consider taking a position in Bloom Energy ($BE**)** to capture surging energy demand driven by new data centers.

Bloom Energy offers a reasonable valuation paired with free cash flow that is projected to double annually over the next few years.

Investors should monitor Bloom Energy closely as rapid revenue growth helps offset its currently low operating margins.

Use this momentum to build exposure to these key artificial intelligence infrastructure players over the near term.

Watch Microsoft Corporation (MSFT) closely around tomorrow's earnings release to evaluate financial performance and growth in its critical cybersecurity segment. The exceptionally strong market sentiment surrounding Broadcom Inc. (AVGO) highlights its notable resilience despite broader market uncertainty. General investors should completely avoid GameStop Corp. (GME), as experts express a distinctly cautious stance and lack any bullish sentiment for the stock.