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Investors should prioritize Palantir (PLTR) as a high-conviction play on the "ontology layer," which serves as a critical, high-moat bridge between raw AI models and actual enterprise decision-making. Focus on the AI Infrastructure theme by targeting software companies that connect models to complex data, as these "middle layer" providers are more defensible than commoditized AI model creators. Look for "Dual-Use" opportunities in the Defense and Industrial sectors, specifically companies that serve both commercial and national security interests to capture a shift away from traditional government-funded contracts. Consider exposure to "picks and shovels" automation tools like Ramp, Vanta, or WorkOS that allow firms to scale operations without increasing headcount. Monitor the U.S. Re-industrialization trend, favoring companies that utilize AI to drive massive productivity gains in domestic manufacturing and supply chain management.

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