For a $100k crypto portfolio, the strategy suggests going all-in on the @megaeth_labs ICO with multiple accounts and selling within 72 hours of Token Generation Event (TGE). Additionally, allocate 90% of the portfolio to @extendedapp and @hyperunit, utilizing Extended for shorting assets and Hyperunit for spot buys, while farming both platforms. The remaining 10% should be used for a sybil farm across 100 wallets.