
Investors should focus on the US Defense Industrial Base, specifically companies solving the 70-million-hour labor deficit in the Navy’s submarine programs. Look for private or public exposure to Hadrian, which is scaling software-driven automated factories to de-risk the supply chain for Columbia-class and Virginia-class submarines. A high-conviction theme is the integration of autonomous systems, where leaders like Anduril and Saronic are developing low-cost underwater drones to act as "payloads" for traditional platforms. Monitor "Advanced Manufacturing Hubs" in the US interior for growth, as the Pentagon shifts toward "software + steel" vendors that can bypass traditional bureaucratic bottlenecks. Prioritize companies achieving "first article" safety approvals, as meeting rigorous nuclear and deep-sea pressure standards is the primary hurdle for new defense tech entrants.
Hadrian is an advanced manufacturing company focused on rebuilding the US defense industrial base through software-driven "automated" factories. The podcast highlights the opening of Factory 4, a 2.25 million square foot facility in Alabama specifically designed to support the Navy’s submarine programs.
The discussion touched upon the shift toward smaller, autonomous, and "attritable" (expendable) underwater drones and how they interact with massive legacy platforms.
The US Navy is undergoing a massive recapitalization of its sea-based nuclear deterrent.
The podcast outlines a broader shift in how the US government is approaching defense procurement.

By Andreessen Horowitz
The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!