
Investors should focus on B2B cross-border fintech in Latin America, where companies like Jeeves are disrupting traditional banking by using stablecoins to settle international payments in one hour instead of days. While Jeeves is currently private, its success highlights a high-conviction shift toward stablecoin-native financial systems that protect enterprise purchasing power in high-inflation markets like Argentina and Brazil. Look for exposure to USDC and MasterCard, as the former provides the liquidity for these "invisible" blockchain rails and the latter serves as the primary infrastructure partner for global expansion. Artificial Intelligence is no longer optional; the highest-margin opportunities lie in firms using AI agents for automated underwriting and reconciliation to achieve 10x revenue growth without increasing headcount. Prioritize fintech investments that own their regulatory licenses and infrastructure, as this "full-stack" approach has proven to double profit margins from 40% to over 80%.

By Andreessen Horowitz
The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!