
Prioritize investing in AI-native startups built from scratch over legacy companies merely layering basic chatbots onto existing workflows.
Focus your capital on businesses utilizing autonomous agents to execute complex, high-value transactions like loan underwriting and auto sales rather than simple customer support.
Target private companies and upcoming IPOs successfully deploying hundreds of thousands of daily per-customer agents to maximize long-term lifetime value, similar to pioneers like Kavak.
Allocate research toward companies developing proprietary evaluation (evals) infrastructure, as rigorous testing frameworks are the primary bottleneck and key to scaling agentic systems.
Avoid traditional enterprises achieving only marginal efficiency gains through superficial AI adoption, as they face imminent disruption by fully autonomous competitors.

By Andreessen Horowitz
The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!