
Investors looking to capitalize on the enterprise artificial intelligence boom should consider positioning themselves in hardware and infrastructure providers that supply the open-source community, as companies increasingly shift 90% of their production workflows away from closed-source alternatives to lower costs. While private startups like Decagon and Sierra prove that application-layer companies can build strong moats by solving complex business logic, public investors should view foundational labs like OpenAI and Anthropic as R&D leaders rather than monopolistic threats to vertical software. Instead of betting on general-purpose frontier models for long-term scale, target enterprise software firms that implement a "glass box" approach for rapid workflow customization and deployment. Watch for upcoming initial public offerings in the enterprise AI space over the next 12 to 24 months, focusing particularly on product-led businesses that effectively transition custom client solutions into scalable core software products.

By Andreessen Horowitz
The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!