
A new "Agent Layer" of proactive AI is emerging, posing a significant long-term threat to established software-as-a-service (SaaS) companies. Investors should be cautious about incumbents like ServiceNow (NOW), Datadog (DDOG), and Salesforce (CRM), whose core business models are at risk. The value of these platforms as a central "system of record" is being challenged by more efficient AI agents that can execute tasks directly for users. Consider re-evaluating long-term positions in these stocks and closely monitor their ability to adapt to this agentic AI trend. This disruption is creating new investment opportunities in key verticals to watch, such as IT Service Management (ITSM) and AI for Site Reliability Engineering (AISRE).

By Andreessen Horowitz
The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!