Capitalize on the structural growth of Bitcoin and Stablecoins by viewing them as essential utility tools for instant, low-cost cross-border payments and digital dollar access in developing markets.

Target investment opportunities in pharmaceutical and healthcare companies that own proprietary data sets, as these firms are uniquely positioned to unlock massive breakthroughs using Artificial Intelligence.

Prioritize physical infrastructure providers and mission-critical service businesses that supply essential real-world needs, such as energy and hospital power generation.

Avoid investing in traditional, non-crypto businesses trying to adopt stablecoins if they lack strong pricing power or possess overly fragile operational models.

Bitcoin (BTC)

• Santiago Santos notes that Bitcoin presented a major aha moment for him by offering a way to move money cross-border faster, better, and cheaper, particularly helping with remittances in developing countries like Mexico where traditional transfer fees can reach 5% to 6%.
• He views Bitcoin's core utility as a non-sovereign digital currency and cross-border settlement tool, stating that people globally have always wanted and will continue to want digital dollars regardless of price fluctuations.

Takeaways

• View Bitcoin primarily through the lens of its utility for cross-border payments and stablecoin adoption rather than just speculative price movements.

Stablecoins

• Stablecoins are highlighted as a killer use case for moving money cross-border instantly and providing digital access to US dollars, especially in regions with high financial friction and inequality like Latin America.
• Santos mentions that while his firm, Inversion, evaluated many traditional non-crypto businesses to see if stablecoins could transform them, they found the traditional business models often too fragile or limited by lack of pricing power.

Takeaways

• Recognize stablecoins as a foundational technology driving real-world financial efficiency, even if traditional companies integrating them still face operational and regulatory hurdles.

Artificial Intelligence (AI) and Tech Infrastructure

• Santos is extremely bullish on AI, describing it as a renaissance that collapses traditional barriers, democratizes creation, and empowers generalists to build and discover without relying on traditional corporate or academic gatekeepers.
• He emphasizes that critical infrastructure remains vital, noting that sectors requiring physical compute, energy, and mission-critical services (such as hospital power generators) will remain strong and essential.
• In healthcare and pharma, Santos is long on pharmaceutical companies with proprietary data sets because AI models can cross-reference data across diverse fields like neuroscience, sleep, and cognition in ways human researchers alone cannot.

Takeaways

• Look for investment opportunities in companies that possess proprietary data sets, particularly in pharmaceutical and healthcare sectors, as they are best positioned to leverage AI for breakthroughs.
• Focus on essential physical infrastructure and "AI-resistant" or AI-enhanced service businesses that manage critical, legally mandated real-world operations.